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Antiestrogenic, antiandrogenic, and aryl hydrocarbon receptor (AhR) agonist activities have also been identified for condensation products of I3C

It was originally isolated from human gastric juice, where it appears to play protective roles for the digestive tract

ABTS: 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) DPPH: 2,2-diphenyl-1-picrylhydrazyl EFSA: European Food Safety Authority ROS: reactive oxygen species SOD: superoxide dismutase TLC: thin-layer chromatography UV: ultraviolet LP, JC, and AV: Conceptualization, Writingoriginal draft, Writingreview & editing