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In the VITACOG trial, high-dose B vitamins in older adults with mild cognitive impairment and elevated homocysteine reduced atrophy in the gray matter regions most vulnerable to Alzheimers disease, with the placebo group losing about 3.7 percent and the treatment group about 0.5 percent over two years

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Researchers studying neurological conditions, cognitive performance, and anxiety mechanisms frequently investigate this class

The Wnt/-catenin pathway is downregulated in the brains of AD patients