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An example of such an interaction comes from the previously discussed study in which germline ATM L2307F mutations were found to be associated with LUAD arising in individuals with a history of light versus heavy smoking, later age of onset, and broad and local somatic features (that is, EGFR mutation and biallelic ATM inactivation, respectively) 177

[2] [1] With neurological involvement: Hydroxocobalamin 1mg intramuscularly on alternate days until no further improvement, then maintenance injections every 2 months

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Its bacteriostatic properties make it suitable for repeated use from a single vial under proper sterile conditions