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As for most other enzymes of the pathway, SIR may be persulfidated, but neither the cysteine affected nor the effect on activity have been explored (Figure 2 and Supplementary Table 2)

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Anxiolytic effects were observed at 100500 g/kg administered intranasally to rats and the effects were comparable to injections of the tranquilizer diazepam (1 mg/kg) [16]

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