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In agreement with the knockdownreconstitution experiments in HEK293T cells, TFG R106C/R106C fibroblasts exhibited defective LLOMe-dependent recruitment of endogenous CHMP1A to damaged lysosomes, which was rescued by re-expression of wild-type TFG but not of TFG(R106C) or TFG(LIR2-mut) (Fig

Grape pomace is a solid organic by-product consisting of grape skin, stem fractions, pulp, and seed, which are discarded in the manufacture of wines or juices and can either be fermented or not [25]

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