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This condition results in anemia because the life span of the affected red blood cells is reduced by about 90%

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GPx-4 plays a crucial role in cellular defense against oxidative stress, primarily by reducing lipid hydroperoxides to their corresponding alcohols and converting free hydrogen peroxide into water, thereby preventing lipid peroxidation of cell membranes

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It supports normal cell proliferation, tissue repair, and red blood cell maturation, processes that are particularly important during periods of growth, training, or recovery