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During wakefulness, especially sleep deprivation, brain glycogen levels decline, while they are replenished during sleep

Nature communications 13(1):1797, 2022

H.KeightleyP

NF- can modulate the activity of neuronal populations, including those expressing pro-opiomelanocortin (POMC) and neuropeptide Y/agouti-related peptide (NPY/AgRP), which are critical for appetite control (45)