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These aberrant cells typically upset the balance between cell proliferation and cell death, resulting in benign tumors that subsequently develop invasive characteristics and manifest symptoms of the disease that range from benign to metastatic (Sung et al., 2021)

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The series of biochemical transformations begins with the sidechain cleavage catalyzed by the cytochrome P450 enzyme CYP11A1 to give pregnenolone (Figure 7)