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Figure 4 Figure 5 7 MERRF and epilepsy MERRF is a rare mitochondrial disorder caused by pathogenic mutations in mtDNA

These results indicate that C75 reduced ROS production by activating the Nrf2/HO-1 pathway, thereby inhibiting NLRP3 inflammasome-mediated pyroptosis

Furthermore, an LA-rich HFD can impair antitumor T-cell responses via the induction of mitochondrial dysfunction

Stimulator of interferon genes (STING) provides insect antiviral immunity by promoting Dredd caspase-mediated NF-B activation

Abstract Introduction Ataxia-Telangiectasia (A-T) is a multi-system disorder that may be associated with endocrine changes, oxidative stress in addition to inflammation