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However, in case of hydrophobic drugs like aspirin, phenacetin and phenobarbital, micronisation actually results in a decrease in the effective surface area of such powders and thus, a fall in the dissolution rate

The peptide's effects on memory consolidation appear mediated through enhanced hippocampal long-term potentiation (LTP), the neurophysiological basis of memory storage, with Dihexa treatment increasing both the magnitude and persistence of synaptic strengthening

This works out to about 6.67 mg/mL of Pinealon in solution

doi: 10.3389/fphar.2021.627533 Received 09 November 2020 Accepted 03 February 2021 Published 29 June 2021 Volume 12 - 2021 Edited by Gabor Varga, Semmelweis University, Hungary Reviewed by Alexandra Mik, University of Pcs, Hungary Zoltn S