Methodology A literature-based search, covering research reports that have been published the last five years, was performed to retrieve information on the chemistry, health effects, molecular pharmacology, herbdrug interaction, nanotechnology-based drug delivery, and safety of black cumin and TQ from accessible online databases, such as PubMed, Web of Science, Scopus, and Google Scholar, using the key search terms of black cumin and chemical constituents, antioxidant, anti-inflammatory, immunomodulatory, neuroprotective, nephroprotective, anti-obesity, cardioprotective, hepatoprotective, anticancer, nanotechnology or toxicity, etc

The European Medicines Agency (EMA) has approved peroral and topical/dermal retinoid-containing medicinal products, which may contain one of the following retinoids: aciretin, adapalene, alitretinoin, bexarotene, isotretinoin, tretinoin, tretinoin, or tazarotene, alone or combined with antibiotics (erythromycin or clindamycine) or benzoyl peroxide (please see the following for different products: EMA/PRAC/461930/2016 Rev 1 [66])
Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway
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The Role of Taurine in the Muscle Phenotype Under Exercise Conditions Taurine increases the muscle level, and this could be due to phenotypic-specific contractile properties (Terrill et al., 2016)