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hormaechei strain was comparable to 2,4-D tested at the same concentrations

& Trope, C

The role of these enzymes in pyrethroid resistance has been validated in vivo utilizing heterologous expression in Drosophila (Pavlidi et al., 2012

This effect is not only assigned to the GSH layer, but also to the presence of extra hydrate layers in aqueous medium

Indeed, a recent review explicitly notes that bacteria exposed to plant-derived phytochemicalsincluding OSCsmay evolve resistance through general stress-response mechanisms such as efflux pump upregulation, enzymatic detoxification, or metabolic remodeling under sublethal exposures (Vaou et al., 2021)