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They use another protein, FOXO4, to keep p53 stuck in the nucleus so it cannot trigger cell death

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Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, et al

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study on Leydig cells found that testosterone recovery in aged mice required weeks of tissue microenvironment improvement following senescent cell clearance (Zhang et al., 2020)