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While mechanistically enigmatic, phenylacetylglutamines robust functional validation demands urgent mechanistic dissection to assess druggability, while serving as a caution against premature clinical extrapolation from correlative findings alone

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While each flavonoid has antimicrobial capabilities against some strains, no antimicrobial impacts have been observed against Streptococcus oralis and Streptococcus sanguinis (341)

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