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While it is important to note that most evidence remains preclinical, the breadth and consistency of findings across different research models provides a strong foundation for understanding the compound therapeutic potential

One aspect of this study that may be missed are the overall excellent responses achieved with only a moderate dose of methotrexate, highlighting the potency of methotrexate as a DMARD which can often be overlooked in clinical trials that typically enroll only subjects with inadequate responses to methotrexate

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The combination accelerates wound closure, reduces inflammation, minimizes scar formation, and promotes proper tissue organization