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The global signal in fMRI: nuisance or information

Results Mice treated with LPS exhibited mitochondrial dysfunction, oxidative stress, an inflammatory response, neural cell apoptosis, and loss of dendritic spines in the hippocampus, leading to impaired hippocampus-related learning and memory performance in the MWM and contextual fear conditioning test

Lab handling should follow established protocols for research compounds, including personal protective equipment and contamination prevention measures

Once liquid is added, the vial becomes a short-term refrigerated research material with tighter sterility, temperature, and handling requirements

1998;92(4):11918 Accessed July 27, 2017