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Yet, in an unrandomized and unblinded trial in patients with multiple myeloma, the administration of SRT501 was associated with a number of serious adverse effects, including kidney failure, such that the trial was halted (77)

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The fluorescence intensity of those pixels was weak compared to high-concentration Nile Red staining (Supplementary Figure S3), although some small lipid particles can be still observed in the gonad region (some of which are indicated by yellow arrowheads in Figure 3F)