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Figure 4 Similarly, combining TLR4/NF-B and Nrf2-ARE pathway modulation offers a comprehensive approach to managing IBD by simultaneously reducing inflammation and enhancing antioxidant defenses

Other relevant interactions: Colchicine (used for gout) may affect B12 absorption with long-term use Chloramphenicol (rarely used antibiotic) may blunt the haematological response to B12 treatment Monitoring considerations: Patients taking loop or thiazide diuretics require careful monitoring when initiating B12 therapy in severe deficiency, due to the risk of hypokalaemia during rapid cell production

Pentadecapeptide BPC 157 and the central nervous system Neural Regeneration Research, 2022 Mar, Volume 17 (Issue 3), Pages 482-487