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PMID: 35003319 Nat Prod Commun2020, 15(8), 1934578X2094625

Lactic acidosis caused by systemic hypoperfusion: While lactic acidosis can occur due to systemic hypoperfusion (e.g., in sepsis or cardiogenic shock), this patients presentation of right-sided heart failure and pulmonary hypertension is more specific for cor pulmonale

Itaconic acid, converted from the decarboxylation of the tricarboxylic acid (TCA) cycle intermediate cis -aconitate, possesses anti-inflammatory functions and emerges as a promising therapeutic target to treat allergic diseases

Research has shown that individuals with low levels of Vitamin B12 are more likely to experience symptoms of depression and anxiety

However, the existing researches on ferroptosis in lung cancer mainly focus on chemical drugs, natural drugs and the combination of drugs and drugs, and there is also a small amount of synergistic effect of drugs with certain therapies