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doi: 10.1016/j.vetmic.2022.109427 43 LiBWanZWangZZuoJXuYHanXet al

16 While the ideal dose of rasburicase for all patients with TLS is suggested to be a single dose of 6mg, studies indicate that a 3mg dose may be adequate for most cases of hyperuricemia

This improvement may be attributed to the prolonged release time and increased the bioavailability of BUD delivered by liposomal nano-vehicles in the body, which enhanced the airway microenvironment for a longer duration and reduced mucus production

The underlying mechanism of such drugs is reported to have a multi-mechanistic or physiological approach through inhibiting the renin-angiotensin system

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