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Weston CR, Davis RJ (2007) The JNK signal transduction pathway

Collectively, these results demonstrate that deletion of Keap1 (and subsequent NRF2 hyperactivation) drives CD8 + T cells toward dysfunction, marked by reduced expansion, diminished effector function and acquisition of a T tex phenotype

Finally, the types, locations, and stages of brain tumors, as well as the therapeutic regimen are also important factors to be considered to hypothesize the desired effect (pro/antioxidant) from an exogenous antioxidant in brain cancer treatment

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Special populations and interactions Older adults sometimes have lower carnitine production and may respond differently to supplementation