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PMID: 37890360 SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

doi: 10.3389/fncel.2024.1371213 15 GalganoM.ToshkeziG.QiuX.RussellT.ChinL.ZhaoL.-R

The G6PD phosphorylation is positively correlated with G6PD-SRC-GSTP1 complex in ER/PR positive type or HER negative types of breast cancer Molecular sub-typing of breast cancer heavily relies on the expression patterns of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER) [50]