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Semin Reprod Med (2019) 37(2):8492

Necrosis occurs mainly in the ischemic core as a result of a severe deficit or absence of oxygen and glucose

Another interesting study found that maternal 25-hydroxy vitamin D (calcifediol) deficiency led to decreased NRF2 and increased ROS in the placenta of pregnant rats as well as in the liver and pancreas of the pups, leading to metabolic syndrome in both mother and offspring (82)

This paradoxical reaction is not fully understood but is thought to be related to individual metabolic responses

At Active Med Integrative Health Center in Encinitas, CA, we are committed to helping our patients achieve optimal lung health through personalized treatment plans