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Kiely AP, Murray CE, Foti SC, Benson BC, Courtney R, Strand C, et al

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Conversely, a chronic increase of ROS can either overwhelm the responsive capacity of these pathways or induce the oxidation of specific components of UPR, UPS, or autophagy, thus exacerbating the accumulation of unfolded/misfolded proteins (333, 334) (FIGURE 9)

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Popovtzer, R

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A prospective cohort study reported that combining sTfR and ferritin into a ratio-based index achieved an area under the curve (AUC) of 0.87 in predicting A-positivity, outperforming traditional individual biomarkers (Du et al., 2024)

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Radford University

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