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4 Mechanistic pathways linking oxidative stress to male infertility 4.1 Lipid peroxidation of sperm membranes and consequences for motility and fusion Spermatozoa are uniquely vulnerable to lipid peroxidation owing to their plasma membranes being enriched with polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA) (77)