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Despite structural similarities to AA-derived eicosanoids, some EPA-derived eicosanoids are potent anti-inflammatory and anti-nociceptive agents

Eur J Neurol 20:515 Figueroa JJ, Singer W, Sandroni P, Sletten DM, Gehrking TL, Gehrking JA, Low P, Basford JR (2015) Effects of patient-controlled abdominal compression on standing systolic blood pressure in adults with orthostatic hypotension

The NF-B signaling pathway, activated in 80% of RA synovium, drives cytokine production, while the Janus kinase (JAK)/signal transducers and activator of transcription (STAT) pathway mediates IL-6 signaling, contributing to chronic inflammation (11)

Dietary fiber intake negatively correlates with depressive symptom severity (Firth et al., 2020)

Gersey ZC, Rodriguez GA, Barbarite E, Sanchez A, Walters WM, Ohaeto KC, et al