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(57) found that mustard gas exposure triggered ROS overproduction, upregulation of the ferroptosis gene ACSL4 promoted lipid peroxidation, and downregulation of SLC7A11 and GPX4 weakened cellular defense

Targeted therapies, including TNF- inhibitors and IL-6 receptor antagonists, effectively reduce inflammation and improve outcomes through cytokine blockade (Smolen, 2020)