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TP53 structure-function relationships in metastatic castrate-sensitive prostate cancer and the impact of APR-246 treatment

To stabilise p53 on protein level, iBACs were treated with 1 M of the pharmacological compound Idasanutlin (Selleck Chemicals, Houston, United States) for 24 h

Finally, similar to the maintenance study, differences were observed with collagen, such that collagen I remained increased around capillaries with PBS injection, but this effect was mitigated with systemic administration of EVs or ExerVs (Fig

Rivas V, Carmona R, Munoz-Chapuli R, Mendiola M, Nogues L, Reglero C, et al

Catalase, a therapeutic target in the reversal of estrogen-mediated aging