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1 The incidence of melasma is increasing among adult women all around the world, said principal investigator Helio Miot, MD, PhD, a Professor of Dermatology at Unesp Botucatu, Sao Paulo state, Brazil, who noted that researchers have hypothesized that contraceptive pills, air pollution, and visible light exposure may be causing this increase

Tinospora cordifolia , another medicinal plant, has been used to relieve the urotoxic effect of cyclophosphamide through the alteration of Glutathione (GSH) and cytokine levels ( Uncaria tomentosa Uncaria tomentosa belongs to the Rubiaceae family, commonly known as ua de gato or cats claw due to its curved hooks (Naseer et al., 2014)