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In addition, low-dose KET has been beneficial on large numbers of patients suffering from oncological and non-oncological pain (Orhurhu et al., 2019)

The role of IL-6 in cachexia-related sarcopenia has been previously discussed in this section and elevated levels of TNF-, IL-6 as well C-reactive protein (CRP) have been detected in sarcopenic people, further suggesting a link between systemic inflammation and muscle degeneration [162, 163]