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Gonsalves, F

doi: 10.1371/journal.pone.0099038

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Of note, neuroinflammation has furthermore been implicated in the pathophysiology of depression [87], whereas increased inflammatory markers, such as C-reactive protein (CRP) or interleukin-2 (IL-2), have been specifically described to be more associated with the atypical subtype of depression [69]

Oxidized PUFA fragments have been hypothesized to destroy membranes and release toxic reactive fragments into cells, which might interfere with other cellular processes [52]