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The EGFRvIII mutation results from a deletion of exons 2 and 7, eliminating the extracellular ligand-binding domain and leading to constitutive receptor activation

Knockdown of ANPEP blocked chronic stressinduced liver cancer progression

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Most in vivo studies administered MG intraperitoneally at 130 mg/kg using repeated or escalating schedules, while in vitro studies employed micromolar or high microgram-per-millilitre concentrations [35]