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Extensive investigation of the molecular pathogenesis of IC can result in the discovery of many novel targets that may assist in the discovery of new drug molecules, majorly including phytochemicals

78 Although ALDH1L1 is overexpressed in NSCLC and GC cancer, 79,80 ALDH1L1 is reported profoundly downregulated or silenced in cancers, rendering it a candidate tumor suppressor

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Phase II takes these highly reactive, dangerous intermediates and binds (conjugates) them to endogenous molecules to neutralize them