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10.1016/j.lfs.2020.118375 174

Q4: Does melasma ever fully go away

References 1 DelgoffeGM

Resistance to cisplatin, but not oxaliplatin, appears to be partly mediated through loss of function in the MMR proteins (hMLH1, hMLH2, or hMSH6), which recognize platinum-DNA adducts and initiate apoptosis