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Mechanistic modeling of primaquine pharmacokinetics, gametocytocidal activity, and mosquito infectivity

Recent studies have made significant progress in understanding its chemical metabolites, pharmacological effects, pharmacokinetics, and safety profiles

In models of retinal neurotoxicity, CBD has been shown to have neuroprotective benefits by directly reducing N-methyl-D-aspartate (NMDA) mediated oxidative stress and maybe by targeting the synthesis of nitro tyrosine, a byproduct of tyrosine nitration (106)