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5.6 Berberine Berberine, an isoquinoline alkaloid (chemical formula C 20 H 18 NO 4 + , molecular weight 336.36 Da), is predominantly isolated from the rhizomes of Coptis chinensis Franch (Ranunculaceae), root bark of Berberis julianae Schneid (Berberidaceae), and bark of Phellodendron amurense Rupr (Rutaceae)

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The metabolic process of APAP in vivo includes the conversion of APAP into the active metabolite NAPQI under the action of Cyp450 [80]

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