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FDA approval Phase 1, 2 and 3 clinical trials require companies to perform extensive clinical studies to determine drug safety and efficacy

Depressed participants were excluded for presence of the following: bipolar disorders, psychotic symptoms, history of psychosis outside of a mood episode, any eating disorder or post-traumatic stress disorder (PTSD) within one month of entering the study, and substance abuse or dependence (including alcohol) within six months of entering the study

Gastroenterology 165 , 515516 (2023)

10.1016/j.freeradbiomed.2023.04.020 24 JiangF

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