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Researchers have found that inflammatory cytokines induce the expression of COX-2 (a chief driver of pain and inflammation among many chronic diseases) in the osteoblasts (cells responsible for the synthesis and mineralization of bones) of inflamed joints

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This process competitively consumes the amino acid substrates available to proteolytic bacteria and shifts metabolism from energy-producing catabolism toward biosynthesis, thereby systematically reducing the production of protein fermentation byproducts

Use of nucleoside (tide) analogues in patients with hepatitis B-related acute liver failure