glutathione and diabetes type 2 Effects of age and/or in levels Efficacy and Safety of Glutathione

Uses Breast, Ovarian, CLL, Non-hodgkins lymphoma, Wilmstumor Busulphan Used in CML Nitrosoureas Carmustine, Lomustine, Streptozocin Mechanism of Action Alkylation (same as other alkylating agents) - Carbamoylation of lysine - No cross-resistance Pharmacokinetics given orally or I/V -non-enzymatic decomposition -highly lipid soluble Toxicity STREPTOZOCIN has minimal bone marrow toxicity Uses Insulinoma, Brain, Lymphomas Platinum Analogs Cisplatin - Inorganic metal complex Mechanism of Action - same as alkylating agents Toxicity general - Nephrotoxicity hydration by oral I/V fluids - Neuropathy - Ototoxicity Uses a

Salim 2014)

Reversed ethanol-induced depletion of hepatic GSH levels

Unlike with oral supplements, due to the breakdown by stomach and enzymes only portion of the medication are absorbed by the body, that weakens its potency and efficacy

Structures of neostigmine & pryidostigmine