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John Wiley & Sons

This duration provides enough cumulative GH stimulation to support muscle protein synthesis, fat metabolism, and sleep quality improvements

Increased GH then triggers the liver to produce IGF-1 (Insulin-like Growth Factor-1), which plays a vital role in muscle growth

The structural comparison indicates that the GHSR-G i complex in our structures resembles the canonical NTSR1-G i state with a similar G i interaction profile (Fig