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Secondary cerebral folate deficiency encompasses conditions such as dihydrofolate reductase deficiency, genetic folate malabsorption, and dihydropteridine reductase deficiency

Administering high doses of biotin (23 mg/kg/d) and thiamine (100300 mg/d) shortly after symptoms onset can lead to complete resolution or remission of symptoms within a few days in the majority of patients

We refer readers to that section for general comments related to the Emergency Care Access & Timeliness eCQM

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Questionable Long-Term Efficacy for Chronic Low Back Pain: A meta-analysis comparing surgical fusion to non-surgical intervention for chronic low back pain found only a marginal, non-statistically significant improvement in the Oswestry Disability Index (ODI) in favor of surgery